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He is currently taking Denazipel and Mamantine since 2021. Are their other medications he can take to slow down the progression besides these two medications?

Even the medications you mentioned are hit or miss as far as helping slowing down the progression, and if they do ever help it's usually only for the first 6 months, so the fact that your husband has been on them for several years now, I'm sure they're not doing anything at this point.
The only medications now that might help are the ones that deal with the different behaviors your husband may exhibit, and you can talk to his neurologist about them if and when needed.
At your husbands young age it sounds like it may be early onset Alzheimer's which sadly can go for 20+ years, as it is the slowest progressing dementia and there is NO stopping it.
I am grateful that my late husband had vascular dementia which is the most aggressive of all the dementias, with a life expectancy of just 5 years, so he nor I had to suffer that long.
All dementias SUCK, and more and more people are being diagnosed with it as the population ages. Perhaps someday we will have a cure, but because there are so many different dementias it will be hard to cure them all.
I wish you well as you travel this long and difficult road with your husband.
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Reply to funkygrandma59
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CMillie65 Aug 16, 2024
Thank you for your advice and kind words. We both are Navy Vets and we both worked in law enforcement. We’ve been married for 38 years and have been together 40. This was suppose be our time to spend traveling and relaxing on the porch and deck. This disease has robbed us of that.
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You could have his Neurologist search to see if there is a Clinical Trial that he might qualify for.
There ae some promising trials being done.
Most of the trials are "double blind" so that the patient nor the people running the trial and giving the medication know if the actual drug is being given so it is somewhat of a "crapshoot" but it might be worth it.
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Reply to Grandma1954
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A Forum of absolute strangers cannot conceivably be familiar with, diagnose or prescribe what medications your hubby should be taking. Sorry, C., but this is a question for you to discuss with the medical team.
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Reply to AlvaDeer
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Brains are complex and handled by specialists. I you hear of a med then consult with the doctor what might tell you that certain meds are absolutely contraindicated. It sounds like you are already working with a good doctor. Ther is no cure and no turning backwards. Just slowing down progression
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